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KMID : 0371319670090050241
Journal of the Korean Surgical Society
1967 Volume.9 No. 5 p.241 ~ p.249
Hypothermic Perfusion in Open Heart Surgery



Abstract
Perfusion data on the initial 40 cases of open heart surgery performed at Yonsei Medical Center is presented. The age of the patients ranged between 6 and 54 years and the body surface area between 0.64 and 1.69 M2. In all cases, a moderate hypothermia of about 30¢¥C was used in conjunction with extracorporeal bypass. Except in the first three cases, the flow rate was adjusted according to the venous return during the perfusion and averaged 1.6L/Min./M2.
Hypothermia was accomplished by both an external cooling by water mattress and an internal cooling by a heat exchanger which is an integral part of the oxygenator system. The time required to bring the esophageal temperature to desired level was 6 minutes on the average and the rewarming time was 14 minutes. This discrepancy is thought to be due to the inlet temperature difference between the blood and the circulating water in the heat exchanger.
The systemic arterial resistance diminished proportionately with the increase in the mean flow rate. The chest tube drainage during the first 24 hours following operation was definitely related both to the total perfusion time and the total perfusion volume, indicating longer perfusion time is accompanied by more postoperative bleeding. Both the cooling and the rewarming rate was proportionately increaed with the increase in the mean flow rate.
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